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ribociclib will enhance the level or effect of fentanyl by affecting hepatic/intestinal enzyme CYP3A4 metabolism.Keep an eye on Closely (one)enasidenib will lower the level or effect of fentanyl by affecting hepatic/intestinal enzyme CYP3A4 metabolism.phenobarbital will lessen the level or effect of fentanyl by affecting hepatic/intestinal enzyme C